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Sun Y, Guan X, Wang H, Zhang J, Gu H, Lu H, et al

Hence, there is a lot of interest in quantifying BDNF isoforms through a validated and reliable methodology, in order to use them as clinical and epidemiological biomarkers

It noted that oral and intra-articular peptides showed distinct advantages in soft tissue regeneration, with intra-articular routes providing localized effects and oral routes offering systemic benefits

These effects are likely partly due to local increases in extracellular glutamate causing excitotoxicity, and reduced trophic support [e.g., platelet-derived growth factor (PDGF)] from astrocytes (Tognatta et al., 2020)

(10) Streeper RS, et al