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Although the MASLD definition differs conceptually from traditional NAFLD criteria, multiple validation studies demonstrate high diagnostic concordance between both classification systems (810)

Furthermore, researchers were unable to identify the DSIP gene, a precursor protein, or a specific receptor for the peptide

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Moreover, at the 2-year follow-up, 64% of participants who maintained a weight loss of 10 kg or more achieved diabetes remission [275]

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