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Several segments in the ECD of GCGR, the stalk between ECD and transmembrane helix 1 (TM1) of GLP-1R (residues 130135), extracellular loop 1 (ECL1) of GIPR (residues 202207), and intracellular loop 3 (ICL3) of GLP-1R and GIPR (residues 338343 and 330333, respectively) were poorly resolved and not modeled in the structures

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Down syndrome : Children with Down syndrome are at a higher risk

Most obesity drugs on the market are formulated as weekly injections

These noncarboxylated clotting factors (termed proteins induced by vitamin K antagonists, or PIVKAs) appear to act as inhibitors of coagulation